Chronic inflammation (as distinct from acute inflammation, which is mostly a healing reaction) is often present for years and is seen in most chronic diseases due primarily to “insulin resistance” from poor nutrition, environmental toxins, and chronic stress. Metabolic inflammation (also known as “Meta-inflammation,”) causes chronic activation of macrophages, which alters the body’s balance of inflammatory cells. Immune cells react abnormally, and the auto-immune response is increased, leading to even more destruction of healthy cells and tissues. Mitochondria are key regulators of inflammation and depend on a healthy diet and microbiome in order to respond appropriately.
These mitochondrial signals probably contribute to the homeostatic role of inflammation, dysregulation of these processes may lead to autoimmune and inflammatory diseases. A potential reason for the increased incidence of these diseases may be changes in mitochondrial function and signaling in response to such recent phenomena as obesity, dietary changes, and other environmental factors.
In order to reduce inflammation you need good nutrition (reduce sugar, grains and seed oils) a healthy microbiome and mitochondrial system. In addition you might consider a few detoxification products.
- Homocysteine Resist
By increasing your intake of B vitamins specifically folate, Vitamin B6 and B12 you can break down homocysteine in the blood an important inflammatory molecule. Some people develop elevated homocystas levels in part from a genetic predisposition. The MTHFR gene which helps regulate homocysteine may be mutated. A high homocysteine can cause heart attaches, stroke, blood clots, cognitive decline and bone fractures. - Molecular Hydrogen
According to current research, molecular hydrogen has been shown to lower inflammation by reducing oxidative stress and suppressing the production of inflammatory factors in the body, making it a potential therapeutic agent for various inflammatory conditions; studies have demonstrated its anti-inflammatory effects in various tissues including the liver, brain, and lungs. - Omega 3-FA
Research has shown that taking 2,000mg of FDA/DHA daily will lower inflammation. - Ketone - Salts (Keto5)
Ketones, in particular B-hydroxybutyrate, are able to moderate inflammation by inhibiting the NLRP3 inflammasome.
